OXCT1 antibody (N-Term)

Catalog No. ABIN2783387

Product Details anti-OXCT1 Antibody

Target: OXCT1 (3-Oxoacid CoA Transferase 1 (OXCT1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Zebrafish (Danio rerio), Guinea Pig, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OXCT1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TLAERIRAGG AGVPAFYTPT GYGTLVQEGG SPIKYNKDGS VAIASKPREV

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against OXCT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human OXCT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 520 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for OXCT1

Target: OXCT1 (3-Oxoacid CoA Transferase 1 (OXCT1))

Alternative Name: OXCT1 (OXCT1 Products)

Synonyms: OXCT antibody, oxct1 antibody, zgc:92003 antibody, wu:fj36f06 antibody, wu:fj48g08 antibody, OXCT1 antibody, oxct antibody, scot antibody, SCOT antibody, 2610008O03Rik antibody, Oxct antibody, Oxct2a antibody, Scot-s antibody, 3-oxoacid CoA-transferase 1 antibody, 3-oxoacid CoA transferase 1a antibody, 3-oxoacid CoA transferase 1 antibody, 3-oxoacid CoA-transferase 1 L homeolog antibody, succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial antibody, OXCT1 antibody, oxct1a antibody, oxct1 antibody, Oxct1 antibody, oxct1.L antibody, MONBRDRAFT_35053 antibody, LOC100414476 antibody

Background: OXCT1 is a member of the 3-oxoacid CoA-transferase gene family. It is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate.This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
Alias Symbols: OXCT, SCOT
Protein Interaction Partner: SUMO2, UBC, MDM2, THOP1, RBBP7, PTPN11, PTMS, NME1, IDH1, HSPD1, MAPK14, ADSS, MTPN, C12orf10, CBX3, C11orf58, WDR1, IQCB1, TMEM189, TMEM9, VMA21, S100A16, TMEM177, SCAF4, SEPT11, SDHAF2, TIMM9, TOR1AIP1, UBXN7, VAPB, SUCLA2, SUCLG1, UQCRFS1P1, UQCRFS1, T
Protein Size: 520

Molecular Weight: 52 kDa

Gene ID: 5019

NCBI Accession: NM_000436, NP_000427

UniProt: P55809

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis