ACAA2 antibody (N-Term)

Catalog No. ABIN2783320

Product Details anti-ACAA2 Antibody

Target: ACAA2 (Acetyl-CoA Acyltransferase 2 (ACAA2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio), Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACAA2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ALLRGVFVVA AKRTPFGAYG GLLKDFTATD LSEFAAKAAL SAGKVSPETV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 91%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against ACAA2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACAA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 397 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ACAA2 antibody (ABIN2783320)

Aboulaich, Vainonen, Strålfors, Vener: "Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes." in: The Biochemical journal, Vol. 383, Issue Pt 2, pp. 237-48, (2004) (PubMed).

Target Details for ACAA2

Target: ACAA2 (Acetyl-CoA Acyltransferase 2 (ACAA2))

Alternative Name: ACAA2 (ACAA2 Products)

Synonyms: DSAEC antibody, fb59b11 antibody, zgc:56036 antibody, wu:fb59b11 antibody, 0610011L04Rik antibody, AI255831 antibody, AI265397 antibody, D18Ertd240e antibody, acetyl-CoA acyltransferase 2 antibody, acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) antibody, acetyl-CoA acyltransferase 2 L homeolog antibody, ACAA2 antibody, Acaa2 antibody, acaa2 antibody, acaa2.L antibody

Background: ACAA2 catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.
Alias Symbols: DSAEC
Protein Interaction Partner: SUMO2, UBC, SGTA, P4HB, H2AFZ, TERT, TMEM65, RTN4, ZFR, TAX1BP3, TOMM40, SF3B4, VDAC2, VDAC1, TP53BP1, TIAL1, VAMP2, PFN1, PRDX1, APP, ACO2, ACAT1, SCP2,
Protein Size: 397

Molecular Weight: 42 kDa

Gene ID: 10449

NCBI Accession: NM_006111, NP_006102

UniProt: P42765

Pathways: Monocarboxylic Acid Catabolic Process