ATP5B antibody (N-Term)
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- Target See all ATP5B Antibodies
- ATP5B (ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, beta Polypeptide (ATP5B))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Pig, Rabbit, Cow, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ATP5B antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- PIKIPVGPET LGRIMNVIGE PIDERGPIKT KQFAPIHAEA PEFMEMSVEQ
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against ATP5B. It was validated on Western Blot and immunohistochemistry. Catalog ABIN973615 can be used a blocking peptide for this product.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ATP5B
- Top Product
- Discover our top product ATP5B Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 529 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Up-regulation of key microRNAs, and inverse down-regulation of their predicted oxidative phosphorylation target genes, during aging in mouse brain." in: Neurobiology of aging, Vol. 32, Issue 5, pp. 944-55, (2011) (PubMed).
: "Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease." in: The Journal of clinical investigation, Vol. 121, Issue 4, pp. 1508-18, (2011) (PubMed).
: "Protein targets for carbonylation by 4-hydroxy-2-nonenal in rat liver mitochondria." in: Journal of proteomics, Vol. 74, Issue 11, pp. 2370-9, (2011) (PubMed).
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Up-regulation of key microRNAs, and inverse down-regulation of their predicted oxidative phosphorylation target genes, during aging in mouse brain." in: Neurobiology of aging, Vol. 32, Issue 5, pp. 944-55, (2011) (PubMed).
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- Target
- ATP5B (ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, beta Polypeptide (ATP5B))
- Alternative Name
- ATP5B (ATP5B Products)
- Synonyms
- atpmb antibody, atpsb antibody, Atpsyn-beta antibody, hm:zehn0534 antibody, im:6793121 antibody, wu:fj38d01 antibody, zgc:111961 antibody, ATPMB antibody, ATPSB antibody, ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide antibody, ATP synthase subunit beta, mitochondrial antibody, ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit antibody, ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide S homeolog antibody, ATP5B antibody, atp5b antibody, Atp5b antibody, LOC100401662 antibody, LOC100635763 antibody, atp5b.S antibody
- Background
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ATP5B is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). ATP5B is the beta subunit of the catalytic core.This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ATPMB, ATPSB, MGC5231
Protein Interaction Partner: FUS, FDX1, ATP5A1, HUWE1, ATPAF2, TRIM63, TRIM55, SPRTN, STAU1, GRSF1, UBC, MDM2, ASB5, ASB11, SUZ12, RNF2, EZH2, BMI1, GBP1, ADRB2, TERT, vpu, UBL4A, WHSC1, VCAM1, PPP1CC, ITGA4, FN1, ESR1, ATF2, BTK, YWHAE, SUMO2, CA9, FMNL1, ATP5O, ATP6V1B2, ATP5C1, AT
Protein Size: 529 - Molecular Weight
- 52 kDa
- Gene ID
- 506
- NCBI Accession
- NM_001686, NP_001677
- UniProt
- P06576
- Pathways
- Proton Transport, Ribonucleoside Biosynthetic Process
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