PTGDS antibody (N-Term)

Catalog No. ABIN2783248

Product Details anti-PTGDS Antibody

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGDS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MATHHTLWMG LALLGVLGDL QAAPEAQVSV QPNFQQDKFL GRWFSAGLAS

Predicted Reactivity: Dog: 86%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 80%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PTGDS. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PTGDS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 190 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTGDS

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Alternative Name: PTGDS (PTGDS Products)

Synonyms: 6PGD antibody, GSTS antibody, GSTS1-1 antibody, PGD2 antibody, PGDS antibody, L-PGDS antibody, LPGDS antibody, PDS antibody, PGDS2 antibody, H-PGDS antibody, Ptgds2 antibody, 21kDa antibody, Ptgs3 antibody, PH2DISO antibody, phosphogluconate dehydrogenase antibody, hematopoietic prostaglandin D synthase antibody, prostaglandin D2 synthase antibody, prostaglandin D2 synthase (brain) antibody, prostaglandin D synthase antibody, prostaglandin D2 synthase 21kDa (brain) antibody, PGD antibody, HPGDS antibody, PTGDS antibody, Hpgds antibody, Ptgds antibody, LOC100009453 antibody

Background: PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation.The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PDS, PGD2, PGDS, PGDS2, LPGDS, L-PGDS
Protein Interaction Partner: PTGDR, HSP90AA1, KRTAP10-3, KRTAP10-7, Hk3, Hk2, ARRB2, ARR3, RARRES3, CAPN1, PTGDS, MLH1, BCAT2, ATXN1, SHBG, CACNA1A, EGFR, PTGFR, PTGER2, PTGER1,
Protein Size: 190

Molecular Weight: 21 kDa

Gene ID: 5730

NCBI Accession: NM_000954, NP_000945

UniProt: P41222