PDHB antibody (N-Term)

Catalog No. ABIN2783247

Product Details anti-PDHB Antibody

Target: PDHB (Pyruvate Dehydrogenase beta (PDHB))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDHB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GLWKKYGDKR IIDTPISEMG FAGIAVGAAM AGLRPICEFM TFNFSMQAID

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PDHB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PDHB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 359 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDHB

Target: PDHB (Pyruvate Dehydrogenase beta (PDHB))

Alternative Name: PDHB (PDHB Products)

Background: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
Alias Symbols: DKFZp564K0164, PHE1B, PDHBD
Protein Interaction Partner: HUWE1, SUMO2, SUMO3, STAU1, MDM2, RNF2, RRAGB, YWHAE, SNRPD1, PCYT2, EIF5, ADRB2, ITGB1, GNB2, FN1, FCER1A, MDC1, ECT2, PDHX, PDHA1, OGDH, RPSA, FBXO6, CAND1, CUL3, UBC, TSC22D1, RAP1B, PFDN1, GRB7, RCC1, CDKN1A, ANXA7, DYRK2, SRRM2, TRIM63, PDHA2, PDHB,
Protein Size: 359

Molecular Weight: 39 kDa

Gene ID: 5162

NCBI Accession: NM_000925, NP_000916

UniProt: P11177

Pathways: Warburg Effect