MAFA antibody (N-Term)

Catalog No. ABIN2783127

Product Details anti-MAFA Antibody

Target: MAFA (Transcription Factor MafA (MAFA))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAFA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KPALEDLYWM SGYQHHLNPE ALNLTPEDAV EALIGSGHHG AHHGAHHPAA

Cross-Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 83%

Predicted Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against MAFA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAFA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 353 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAFA

Target: MAFA (Transcription Factor MafA (MAFA))

Alternative Name: MAFA (MAFA Products)

Synonyms: RIPE3b1 antibody, hMafA antibody, RGD1562627 antibody, 2F1-Ag antibody, MAFA antibody, MAFA-L antibody, SMaf1 antibody, mafl antibody, L-MAF antibody, MAFL antibody, Maf antibody, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) antibody, MAF bZIP transcription factor A antibody, killer cell lectin-like receptor subfamily G, member 1 antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa antibody, monocyte to macrophage differentiation-associated antibody, Mafa antibody, MAFA antibody, Klrg1 antibody, mafa antibody, mafaa antibody, Mmd antibody

Background: MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS).MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS, MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1062 AC105118.23 99326-100387 c
Alias Symbols: RIPE3b1, hMafA
Protein Interaction Partner: Mapk14, UBC, SUMO1, NEUROD1, PDX1, MAF, MAPK1,
Protein Size: 353

Molecular Weight: 37 kDa

Gene ID: 389692

NCBI Accession: NM_201589, NP_963883

UniProt: Q8NHW3

Pathways: Hormone Transport