PTPLAD1 antibody (N-Term)

Catalog No. ABIN2782887

Product Details anti-PTPLAD1 Antibody

Target: PTPLAD1 (Protein tyrosine Phosphatase-Like A Domain Containing 1 (PTPLAD1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Horse, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPLAD1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WLDESDAEME LRAKEEERLN KLRLESEGSP ETLTNLRKGY LFMYNLVQFL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PTPLAD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PTPLAD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 362 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PTPLAD1 antibody (ABIN2782887)

Taguwa, Okamoto, Abe, Mori, Suzuki, Moriishi, Matsuura: "Human butyrate-induced transcript 1 interacts with hepatitis C virus NS5A and regulates viral replication." in: Journal of virology, Vol. 82, Issue 6, pp. 2631-41, (2008) (PubMed).

Target Details for PTPLAD1

Target: PTPLAD1 (Protein tyrosine Phosphatase-Like A Domain Containing 1 (PTPLAD1))

Alternative Name: PTPLAD1 (PTPLAD1 Products)

Synonyms: B-IND1 antibody, HACD3 antibody, HSPC121 antibody, 4930523M17Rik antibody, AW742319 antibody, B-ind1 antibody, Hspc121 antibody, RGD1565496 antibody, HACD antibody, 3-hydroxyacyl-CoA dehydratase 3 antibody, HACD3 antibody, Hacd3 antibody

Background: PTPLAD1 is a multi-pass membrane protein. It belongs to the PTPLA family and contains 1 CS domain. PTPLAD1 (hB-ind1) plays a crucial role in HCV RNA replication and the propagation of JFH1 virus through interaction with viral and host proteins. It is involved in Rac1-signaling pathways leading to the modulation of gene expression.
Alias Symbols: B-IND1, FLJ90376, HSPC121, HACD3
Protein Interaction Partner: FANCI, BZW2, ATP2B1, ATP2A2, STAU1, PEX19, UBC, LGR4, BMI1, HECW2, CLN3, env, UBL4A, NOS2, CFTR, ESR1, CHCHD6, FAF2, HSPA1L, CUL3, CAND1, GABARAPL2, RAC1, C20orf24, BRF2, PELO, TSPAN17, SERINC3, NEK6,
Protein Size: 362

Molecular Weight: 43 kDa

Gene ID: 51495

NCBI Accession: NM_016395, NP_057479

UniProt: Q9P035