COQ2 antibody (Middle Region)
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- Target See all COQ2 Antibodies
- COQ2 (Coenzyme Q2 Homolog, Prenyltransferase (COQ2))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Pig, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio), Dog, Goat, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This COQ2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- FSGVMWTLIY DTIYAHQDKR DDVLIGLKST ALRFGENTKP WLSGFSVAML
- Predicted Reactivity
- Dog: 93%, Goat: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 93%, Rat: 86%, Yeast: 91%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against COQ2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human COQ2
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 384 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 26, Issue 11-12, pp. 619-29, (2015) (PubMed).
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New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 26, Issue 11-12, pp. 619-29, (2015) (PubMed).
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- Target
- COQ2 (Coenzyme Q2 Homolog, Prenyltransferase (COQ2))
- Alternative Name
- COQ2 (COQ2 Products)
- Synonyms
- CG9613 antibody, COQ2 antibody, Dmel\\CG9613 antibody, coq2 antibody, sbo antibody, CL640 antibody, COQ10D1 antibody, MSA1 antibody, RGD1306722 antibody, zgc:162600 antibody, 2310002F18Rik antibody, Coenzyme Q biosynthesis protein 2 antibody, coenzyme Q2, polyprenyltransferase antibody, coenzyme Q2 4-hydroxybenzoate polyprenyltransferase antibody, 4-hydroxybenzoate polyprenyltransferase, mitochondrial antibody, Coq2 antibody, COQ2 antibody, coq2 antibody, coq-2 antibody
- Background
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COQ2 catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. COQ2 mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB.CoQ (ubiquinone) serves as a redox carrier in the mitochondrial respiratory chain and is a lipid-soluble antioxidant. COQ2, or parahydroxybenzoate-polyprenyltransferase (EC 2.5.1.39), catalyzes one of the final reactions in the biosynthesis of CoQ, the prenylation of parahydroxybenzoate with an all-trans polyprenyl group (Forsgren et al., 2004 [PubMed 15153069]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-90 BC020728.1 1-90 91-96 BG699931.1 80-85 97-789 BC020728.1 97-789 790-792 BQ363759.1 169-171 793-1535 BC020728.1 793-1535 1536-1554 BC008804.2 1496-1514
Alias Symbols: CL640, FLJ26072
Protein Interaction Partner: UBC,
Protein Size: 384 - Molecular Weight
- 42 kDa
- Gene ID
- 27235
- NCBI Accession
- NM_015697, NP_056512
- UniProt
- Q96H96
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