Seladin 1 antibody (Middle Region)

Catalog No. ABIN2782832

Product Details anti-Seladin 1 Antibody

Target: Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Seladin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AELYIDIGAY GEPRVKHFEA RSCMRQLEKF VRSVHGFQML YADCYMNREE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against DHCR24. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DHCR24

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 516 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Seladin 1

Target: Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))

Alternative Name: DHCR24 (DHCR24 Products)

Synonyms: MGC82737 antibody, zgc:101638 antibody, DCE antibody, Nbla03646 antibody, SELADIN1 antibody, seladin-1 antibody, 2310076D10Rik antibody, 5830417J06Rik antibody, mKIAA0018 antibody, 24-dehydrocholesterol reductase antibody, 24-dehydrocholesterol reductase S homeolog antibody, delta(24)-sterol reductase antibody, DHCR24 antibody, dhcr24.S antibody, dhcr24 antibody, LOC5575872 antibody, CpipJ_CPIJ000670 antibody, Dhcr24 antibody

Background: DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endopla
Alias Symbols: KIAA0018, Nbla03646, SELADIN1, seladin-1, DCE
Protein Interaction Partner: UBC, env, UBL4A, TP53, MDM2,
Protein Size: 516

Molecular Weight: 58 kDa

Gene ID: 1718

NCBI Accession: NM_014762, NP_055577

UniProt: Q15392