Myoferlin antibody (C-Term)
-
- Target See all Myoferlin (MYOF) Antibodies
- Myoferlin (MYOF)
-
Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Cow, Rabbit, Rat, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Myoferlin antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- QTEFRIPPRL IIQIWDNDKF SLDDYLGFLE LDLRHTIIPA KSPEKCRLDM
- Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against FER1L3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human FER1L3
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 2061 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- Myoferlin (MYOF)
- Alternative Name
- FER1L3 (MYOF Products)
- Synonyms
- FER1L3 antibody, 2310004N10Rik antibody, 2310051D19Rik antibody, E030042N20Rik antibody, Fer1l3 antibody, RGD1564216 antibody, zgc:63504 antibody, fer1l3 antibody, myoferlin antibody, MYOF antibody, Myof antibody, myof antibody, LOC100380767 antibody
- Background
-
Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. FER1L3 is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length natures have not been determined.
Alias Symbols: FLJ36571, FLJ90777, MYOF, FER1L3
Protein Interaction Partner: UBC, SUMO2, SUMO3, RPA3, RPA2, RPA1, MATR3, ILF2, ATP6V1B1, CDK2, Kdr, Dnm2, ISG15, SUMO1,
Protein Size: 2061 - Molecular Weight
- 235 kDa
- Gene ID
- 26509
- NCBI Accession
- NM_013451, NP_038479
- UniProt
- Q9NZM1
-