CKAP4 antibody (Middle Region)

Catalog No. ABIN2782739

Product Details anti-CKAP4 Antibody

Target: CKAP4 (Cytoskeleton-Associated Protein 4 (CKAP4))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CKAP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SDGIHVVKDA RERDFTSLEN TVEERLTELT KSINDNIAIF TEVQKRSQKE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CKAP4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CKAP4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 602 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CKAP4 antibody (ABIN2782739)

Clark, Nosie, Walker, Faralli, Filla, Barrett-Wilt, Peters: "Comparative genomic and proteomic analysis of cytoskeletal changes in dexamethasone-treated trabecular meshwork cells." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 1, pp. 194-206, (2012) (PubMed).

Target Details for CKAP4

Target: CKAP4 (Cytoskeleton-Associated Protein 4 (CKAP4))

Alternative Name: CKAP4 (CKAP4 Products)

Synonyms: MGC115278 antibody, MGC147359 antibody, CLIMP-63 antibody, ERGIC-63 antibody, p63 antibody, 5630400A09Rik antibody, P63 antibody, LPC-1 antibody, cytoskeleton associated protein 4 antibody, cytoskeleton-associated protein 4 L homeolog antibody, cytoskeleton-associated protein 4 antibody, zgc:85975 antibody, CKAP4 antibody, ckap4.L antibody, ckap4 antibody, zgc:85975 antibody, Ckap4 antibody

Background: CKAP4/p63 is a substrate of DHHC2, a putative tumor suppressor. CK MNF116 and p63 were useful in identifying squamous cell carcinomas with single cell infiltration. Those results suggested a role of CKAP4/p63 in tumor.
Alias Symbols: CLIMP-63, ERGIC-63, MGC99554, p63
Protein Interaction Partner: FUS, UBC, TP53, SPRTN, SUMO1, NEDD8, MDM2, PARK2, ADRA1D, THOC7, HAMP, env, CCDC53, CKAP4, MVP, TSNAX, NKX3-1, NDUFB7, MYC, MLH1, ATF4, ECT2, COPS5, CUL3, SH3KBP1, ARRB1, ELAVL1, HDGF, CLN3, USP50, ASCC2, PLAT,
Protein Size: 602

Molecular Weight: 66 kDa

Gene ID: 10970

NCBI Accession: NM_006825, NP_006816

UniProt: Q07065