BCAP31 antibody (Middle Region)

Catalog No. ABIN2782693

Product Details anti-BCAP31 Antibody

Target: BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAP31 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: STKQKLEKAE NQVLAMRKQS EGLTKEYDRL LEEHAKLQAA VDGPMDKKEE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against BCAP31. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BCAP31

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 246 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BCAP31

Target: BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

Alternative Name: BCAP31 (BCAP31 Products)

Synonyms: 6c6-ag antibody, bap31 antibody, cdm antibody, dxs1357e antibody, BCAP31 antibody, Bap31 antibody, 6C6-AG antibody, BAP31 antibody, CDM antibody, DXS1357E antibody, CALD1 antibody, caldesmon antibody, si:bz30i22.4 antibody, si:rp71-30i22.4 antibody, zgc:56389 antibody, B-cell receptor associated protein 31 antibody, receptor-associated protein antibody, lipopeptide mating pheromone precursor bap3-1 antibody, B cell receptor associated protein 31 antibody, B-cell receptor-associated protein 31 antibody, B-cell receptor associated protein 31 L homeolog antibody, bcap31 antibody, BAP31 antibody, bap3-1 antibody, BCAP31 antibody, Bcap31 antibody, bcap31.L antibody

Background: BCAP31 is a member of the B-cell receptor associated protein 31 superfamily. It is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in the caspase 8-mediated apoptosis. Microdeletions in this gene are associated with the contiguous ABCD1/DXS1375E deletion syndrome.
Alias Symbols: 6C6-AG, BAP31, CDM, DXS1357E
Protein Interaction Partner: GPRIN2, UBC, COX2, ITGAM, RPA3, RPA2, RPA1, YWHAQ, ATP4A, env, PGRMC1, UBL4A, KLK10, SERPINF2, ATF2, CASP8, CANX, VKORC1, nef, APP, Htt, PTPLB, FIS1, MYH10, HLA-A, BCL2L1, ACTG1, DERL1, BCAP29, BFAR, SEC61A1, TRAM1, SEC61B, BCAP31, RNF5, LMAN1, CFTR, Copa
Protein Size: 246

Molecular Weight: 28 kDa

Gene ID: 10134

NCBI Accession: NM_005745, NP_005736

UniProt: P51572

Pathways: Positive Regulation of Endopeptidase Activity