DNASE1 antibody (N-Term)

Catalog No. ABIN2782673

Product Details anti-DNASE1 Antibody

Target: DNASE1 (Deoxyribonuclease I (DNASE1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNASE1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GKLLDNLNQD APDTYHYVVS EPLGRNSYKE RYLFVYRPDQ VSAVDSYYYD

Predicted Reactivity: Cow: 79%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against DNASE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DNASE1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 282 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DNASE1

Target: DNASE1 (Deoxyribonuclease I (DNASE1))

Alternative Name: DNASE1 (DNASE1 Products)

Background: This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1
Alias Symbols: DKFZp686H0155, DNL1, DRNI, FLJ38093, FLJ44902
Protein Interaction Partner: ACTA1, ACTB, ACTA2, ACTG1,
Protein Size: 282

Molecular Weight: 31 kDa

Gene ID: 1773

NCBI Accession: NM_005223, NP_005214

UniProt: P24855