DDOST antibody (N-Term)
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- Target See all DDOST Antibodies
- DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DDOST antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SPSVEDFGGN INVETISAFI DGGGSVLVAA SSDIGDPLRE LGSECGIEFD
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against DDOST. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human DDOST
- Top Product
- Discover our top product DDOST Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 456 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))
- Alternative Name
- DDOST (DDOST Products)
- Synonyms
- AGER1 antibody, CDG1R antibody, OKSWcl45 antibody, OST antibody, OST48 antibody, WBP1 antibody, DDOST antibody, wu:fa11d01 antibody, zgc:66068 antibody, zgc:77478 antibody, Ddost antibody, CG9022 antibody, DmOST50 antibody, Dmel\\CG9022 antibody, DrOST antibody, OST48/WBP1 antibody, Ots48 antibody, anon-EST:Liang-1.11 antibody, clone 1.11 antibody, ost48 antibody, dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit antibody, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) S homeolog antibody, dolichyl-diphosphooligosaccharide-protein glycosyltransferase antibody, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) antibody, dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit antibody, dolichyl-di-phosphooligosaccharide-protein glycotransferase antibody, Oligosaccharyltransferase 48kD subunit antibody, DDOST antibody, ddost.S antibody, GTR26 antibody, ddost antibody, Ddost antibody, LOC5580056 antibody, PTRG_01946 antibody, Ost48 antibody
- Background
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DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
Alias Symbols: AGE-R1, KIAA0115, MGC2191, OK/SW-cl.45, OST, OST48, WBP1, AGER1, OKSWcl45
Protein Interaction Partner: HUWE1, VAPB, UBC, FAF1, STAU1, ASB11, TRIM13, SUZ12, EED, CLN3, NXT1, SRSF11, FN1, ATF2, STT3B, MAGT1, ZMPSTE24, VDAC2, SSR4, SSR3, SLC25A3, ILF2, KRTCAP2, FBXO6, UBD, AMFR, AUP1, TMEM173, UNC93B1, MAPK6, HDAC5, AGO3, BRCC3, GSTK1, TMBIM4, PGRMC1, SAP18,
Protein Size: 456 - Molecular Weight
- 46 kDa
- Gene ID
- 1650
- NCBI Accession
- NM_005216, NP_005207
- UniProt
- Q5VWA5
- Pathways
- Cell RedoxHomeostasis
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