NDST3 antibody (N-Term)

Catalog No. ABIN2782656

Product Details anti-NDST3 Antibody

Target: NDST3 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 3 (NDST3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDST3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PGTDWTVFQI NHSAYQPVIF AKVKTPENLS PSISKGAFYA TIIHDLGLHD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NDST3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NDST3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 873 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NDST3

Target: NDST3 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 3 (NDST3))

Alternative Name: NDST3 (NDST3 Products)

Synonyms: NDST3 antibody, HSST3 antibody, 4921531K01Rik antibody, 4930511P15Rik antibody, N-deacetylase and N-sulfotransferase 3 antibody, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 antibody, NDST3 antibody, ndst3 antibody, LOC100484094 antibody, LOC100539813 antibody, Ndst3 antibody

Background: NDST3 is a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. NDST3 is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin.
Alias Symbols: MGC130028, MGC130029, HSST3
Protein Size: 873

Molecular Weight: 101 kDa

Gene ID: 9348

NCBI Accession: NM_004784, NP_004775

UniProt: O95803

Pathways: Glycosaminoglycan Metabolic Process