ECM1 antibody (Middle Region)

Catalog No. ABIN2782635

Product Details anti-ECM1 Antibody

Target: ECM1 (Extracellular Matrix Protein 1 (ECM1))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECM1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Sequence: QDRSQGGWGH RLDGFPPGRP SPDNLNQICL PNRQHVVYGP WNLPQSSYSH

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ECM1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ECM1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ECM1

Target: ECM1 (Extracellular Matrix Protein 1 (ECM1))

Alternative Name: ECM1 (ECM1 Products)

Synonyms: URBWD antibody, ECM antibody, EMILIN4 antibody, GPIa* antibody, MMRN antibody, AI663821 antibody, p85 antibody, extracellular matrix protein 1 antibody, multimerin 1 antibody, ECM1 antibody, MMRN1 antibody, Ecm1 antibody

Background: This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.
Alias Symbols: -
Protein Interaction Partner: IL2RB, HECW2, SRPK1, CPTP, IRAK3, BNIP3L, ATN1, RERE, UBC, HSPG2, FBLN1,
Protein Size: 170

Molecular Weight: 18 kDa

Gene ID: 1893

NCBI Accession: NM_022664, NP_073155