CPT1B antibody (Middle Region)

Catalog No. ABIN2782633

Product Details anti-CPT1B Antibody

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPT1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DLEMQFQRIL DDPSPPQPGE EKLAALTAGG RVEWAQARQA FFSSGKNKAA

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against CPT1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CPT1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 772 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CPT1B antibody (ABIN2782633)

Fiserova, Trinh, Elkalaf, Vacek, Heide, Martinkova, Bechynska, Kosek, Hajslova, Fiser, Tousek, Polak: "Isoprenaline modified the lipidomic profile and reduced β-oxidation in HL-1 cardiomyocytes: In vitro model of takotsubo syndrome." in: Frontiers in cardiovascular medicine, Vol. 9, pp. 917989, (2022) (PubMed).

Jiang, Ma, Li, Cao, Wang, Zhang, Liu: "Effects of neonatal dexamethasone administration on cardiac recovery ability under ischemia-reperfusion in 24-wk-old rats." in: Pediatric research, Vol. 80, Issue 1, pp. 128-35, (2016) (PubMed).

Li, Liu, Ma, Guan, Cao, Tian, Zhang: "Enhancement of Glucose Metabolism via PGC-1α Participates in the Cardioprotection of Chronic Intermittent Hypobaric Hypoxia." in: Frontiers in physiology, Vol. 7, pp. 219, (2016) (PubMed).

Wolf-Johnston, Hanna-Mitchell, Buffington, Shinde, Roppolo, Mayer, Birder: "Alterations in the non-neuronal acetylcholine synthesis and release machinery in esophageal epithelium." in: Life sciences, Vol. 91, Issue 21-22, pp. 1065-9, (2012) (PubMed).

Target Details for CPT1B

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Alternative Name: CPT1B (CPT1B Products)

Synonyms: CPT1-M antibody, CPT1M antibody, CPTI antibody, CPTI-M antibody, M-CPT1 antibody, MCCPT1 antibody, MCPT1 antibody, CPT-IB antibody, M-CPTI antibody, CPT1 antibody, CPTIB antibody, cpt1al antibody, zgc:103709 antibody, CPT1B antibody, MGC147544 antibody, Cpt1 antibody, Cpt1-m antibody, Cpti antibody, Cpti-m antibody, M-cpti antibody, carnitine palmitoyltransferase 1B antibody, carnitine palmitoyltransferase 1B (muscle) antibody, carnitine palmitoyltransferase 1B L homeolog antibody, carnitine palmitoyltransferase 1b, muscle antibody, CPT1B antibody, Cpt1b antibody, cpt1b antibody, cpt1b.L antibody

Background: The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-
Alias Symbols: CPT1-M, KIAA1670, M-CPT1, CPTI, CPT1M, MCPT1, CPTI-M, MCCPT1
Protein Interaction Partner: C2orf57,
Protein Size: 772

Molecular Weight: 88 kDa

Gene ID: 1375

NCBI Accession: NM_004377, NP_004368

UniProt: Q92523

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process