CHST2 antibody (Middle Region)
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- Target See all CHST2 Antibodies
- CHST2 (Carbohydrate (N-Acetylglucosamine-6-O) Sulfotransferase 2 (CHST2))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHST2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VFQLYSPAGS GGRNLTTLGI FGAATNKVVC SSPLCPAYRK EVVGLVDDRV
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Chst2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product CHST2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 530 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CHST2 (Carbohydrate (N-Acetylglucosamine-6-O) Sulfotransferase 2 (CHST2))
- Alternative Name
- Chst2 (CHST2 Products)
- Synonyms
- chst2 antibody, wu:fj55f04 antibody, zgc:154070 antibody, CHST2 antibody, C6ST antibody, GST-2 antibody, GST2 antibody, Gn6ST-1 antibody, glcNAc6ST-1 antibody, AI428561 antibody, AW121776 antibody, C130041E03Rik antibody, Chts2 antibody, GlcNAc6ST antibody, Gn6st antibody, carbohydrate sulfotransferase 2 antibody, carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2a antibody, carbohydrate sulfotransferase 4 antibody, carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 antibody, carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 L homeolog antibody, CHST2 antibody, chst2a antibody, CHST4 antibody, chst2 antibody, chst2.L antibody, Chst2 antibody
- Background
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Chst2 catalyzes the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as L-selectin ligands. L-selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Chst2 participates in biosynthesis of L-selectin ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. It has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. It sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains.
Alias Symbols: AI428561, AW121776, C130041E03Rik, Chts2, GST-2, GlcNAc6ST, Gn6st
Protein Size: 530 - Molecular Weight
- 58 kDa
- Gene ID
- 54371
- NCBI Accession
- NM_018763, NP_061233
- UniProt
- Q80WV3
- Pathways
- Glycosaminoglycan Metabolic Process
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