SGCE antibody (N-Term)

Catalog No. ABIN2782610

Product Details anti-SGCE Antibody

Target: SGCE (Sarcoglycan, epsilon (SGCE))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGCE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TVYSIFSKVH SDRNVYPSAG VLFVHVLERE YFKGEFPPYP KPGEISNDPI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SGCE. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SGCE

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 462 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SGCE

Target: SGCE (Sarcoglycan, epsilon (SGCE))

Alternative Name: SGCE (SGCE Products)

Synonyms: scge antibody, zgc:92318 antibody, DYT11 antibody, ESG antibody, e-SG antibody, sarcoglycan, epsilon antibody, sarcoglycan epsilon S homeolog antibody, sarcoglycan epsilon antibody, sgce antibody, sgce.S antibody, SGCE antibody, Sgce antibody

Background: SGCE is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with myoclonus-dystonia syndrome. Alternative splicing results in multiple transcript variants.The SGCE gene encodes the epsilon member of the sarcoglycan family, transmembrane components of the dystrophin-glycoprotein complex, which links the cytoskeleton to the extracellular matrix.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DYT11, ESG
Protein Interaction Partner: CWC15, PPP1CC, UBC, ARIH2,
Protein Size: 462

Molecular Weight: 52 kDa

Gene ID: 8910

NCBI Accession: NM_001099401, NP_001092871

UniProt: B5MDA7