ST3GAL5 antibody (N-Term)

Catalog No. ABIN2782609

Product Details anti-ST3GAL5 Antibody

Target: ST3GAL5 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 5 (ST3GAL5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Pig, Rabbit, Cow, Dog, Goat, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST3GAL5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DSEAESKYDP PFGFRKFSSK VQTLLELLPE HDLPEHLKAK TCRRCVVIGS

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against ST3GAL5. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ST3GAL5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 418 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ST3GAL5

Target: ST3GAL5 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 5 (ST3GAL5))

Alternative Name: ST3GAL5 (ST3GAL5 Products)

Synonyms: SATI antibody, SIAT9 antibody, SIATGM3S antibody, ST3GalV antibody, ST3GAL-V antibody, 3S-T antibody, Siat9 antibody, [a]2 antibody, ST3 beta-galactoside alpha-2,3-sialyltransferase 5 antibody, ST3GAL5 antibody, St3gal5 antibody

Background: Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. ST3GAL5 is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. It is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in its gene has been associated with Amish infantile epilepsy syndrome.Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus.
Alias Symbols: SIAT9, SIATGM3S, ST3GalV, SATI
Protein Size: 418

Molecular Weight: 48 kDa

Gene ID: 8869

NCBI Accession: NM_003896, NP_003887

UniProt: Q6NZX4