CENPM antibody (Middle Region)

Catalog No. ABIN2782583

Product Details anti-CENPM Antibody

Target: CENPM (Centromere Protein M (CENPM))

Binding Specificity: Middle Region

Reactivity: Human, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPM antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: CDLEVEGFRA TMAQRLVRVL QICAGHVPGV SALNLLSLLR SSEGPSLEDL

Predicted Reactivity: Cow: 79%, Dog: 79%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 93%

Characteristics: This is a rabbit polyclonal antibody against CENPM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CENPM

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 180 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CENPM

Target: CENPM (Centromere Protein M (CENPM))

Alternative Name: CENPM (CENPM Products)

Synonyms: C22orf18 antibody, CENP-M antibody, PANE1 antibody, bK250D10.2 antibody, 2610019I03Rik antibody, AI853711 antibody, Pane1 antibody, RGD1307309 antibody, centromere protein M antibody, centromere protein M L homeolog antibody, Centromere protein M antibody, centromere protein M pseudogene antibody, CENPM antibody, Cenpm antibody, cenpm antibody, cenpm.L antibody, LOC100353362 antibody

Background: The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA replaces histone H3. CENPM is an additional factor required for centromere assembly.The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM].
Alias Symbols: C22orf18, CENP-M, MGC861, PANE1, bK250D10.2
Protein Interaction Partner: CENPP, CENPL, CENPT, CENPU, CENPO, CENPK, CENPN, CENPQ, CENPI, CENPC, CENPA, UBC,
Protein Size: 180

Molecular Weight: 20 kDa

Gene ID: 79019

NCBI Accession: NM_024053, NP_076958

UniProt: Q9NSP4