PSAT1 antibody (N-Term)

Catalog No. ABIN2782576

Product Details anti-PSAT1 Antibody

Target: PSAT1 (phosphoserine Aminotransferase 1 (PSAT1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: ADYVVTGAWS AKAAEEAKKF GTINIVHPKL GSYTKIPDPS TWNLNPDASY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PSAT1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PSAT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 370 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PSAT1 antibody (ABIN2782576)

Yoon, Kim, Seo, Park, Kim, Park, Choi, Jeong, Jun, Yoon, Kang: "Clinical Implication of Serine Metabolism-Associated Enzymes in Colon Cancer." in: Oncology, Vol. 89, Issue 6, pp. 351-9, (2015) (PubMed).

Yang, Wu, Cai, He, Yuan, Zhu, Li, Li, Guan: "PSAT1 regulates cyclin D1 degradation and sustains proliferation of non-small cell lung cancer cells." in: International journal of cancer, Vol. 136, Issue 4, pp. E39-50, (2014) (PubMed).

Target Details for PSAT1

Target: PSAT1 (phosphoserine Aminotransferase 1 (PSAT1))

Alternative Name: PSAT1 (PSAT1 Products)

Synonyms: fi15b02 antibody, wu:fi15b02 antibody, zgc:55738 antibody, zgc:77622 antibody, EPIP antibody, PSA antibody, PSAT antibody, D8Ertd814e antibody, Psat antibody, Psa1 antibody, phosphoserine aminotransferase 1 antibody, phosphoserine aminotransferase 1 L homeolog antibody, psat1 antibody, psat1.L antibody, PSAT1 antibody, Psat1 antibody

Background: PSAT1 is likely a phosphoserine aminotransferase, based on similarity to proteins in mouse, rabbit, and Drosophila.The protein encoded by this gene is likely a phosphoserine aminotransferase, based on similarity to proteins in mouse, rabbit, and Drosophila. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: EPIP, MGC1460, PSA, PSAT
Protein Interaction Partner: UBC, NEDD8, PPID, PNP, HPRT1, UBD, BAG3, PSMD10, HSP90AB1, HSP90AA1, CEBPE, TUBB6, THADA, KIAA1598, AHCYL1, TTC1, TALDO1, STAT6, RAC1, FH, APP, ACAT2, CDK2, MAPK6,
Protein Size: 370

Molecular Weight: 40 kDa

Gene ID: 29968

NCBI Accession: NM_058179, NP_478059

UniProt: Q9Y617

Pathways: Warburg Effect