TSR1 antibody (Middle Region)

Catalog No. ABIN2782565

Product Details anti-TSR1 Antibody

Target: TSR1 (TSR1, 20S rRNA Accumulation, Homolog (TSR1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSR1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MALVATVYAP ITFPPASVLL FKQKSNGMHS LIATGHLMSV DPDRMVIKRV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against TSR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TSR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 804 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TSR1 antibody (ABIN2782565)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for TSR1

Target: TSR1 (TSR1, 20S rRNA Accumulation, Homolog (TSR1))

Alternative Name: TSR1 (TSR1 Products)

Synonyms: AU040765 antibody, AW550801 antibody, mKIAA1401 antibody, TSR1 20S rRNA accumulation antibody, TSR1, ribosome maturation factor L homeolog antibody, TSR1, ribosome maturation factor antibody, Tsr1 antibody, tsr1.L antibody, TSR1 antibody

Background: TSR1 belongs to the BMS1/TSR1 family and TSR1 subfamily. TSR1 is required during maturation of the 40S ribosomal subunit in the nucleolus.
Alias Symbols: FLJ10534, KIAA1401, MGC131829
Protein Interaction Partner: UBC, TARBP2, FTSJ3, LIN28A, RPA3, RPA2, RPA1, WIBG, WDR26, PNO1, SERBP1, KIAA0368, RANBP9, RPS29, RPS28, RPS27, RPS26, RPS25, RPS24, RPS23, RPS20, RPS19, RPS18, RPS16, RPS15A, RPS14, RPS13, RPS12, RPS10, RPS9, RPS8, RPS7, RPS6, RPS5, RPS4X, RPS3A, RPS3, R
Protein Size: 804

Molecular Weight: 92 kDa

Gene ID: 55720

NCBI Accession: NM_018128, NP_060598

UniProt: Q2NL82

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly