WBP11 antibody (N-Term)

Catalog No. ABIN2782558

Product Details anti-WBP11 Antibody

Target: WBP11 (WW Domain Binding Protein 11 (WBP11))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WBP11 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Sequence: GRRSTSSTKS GKFMNPTDQA RKEARKRELK KNKKQRMMVR AAVLKMKDPK

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against WBP11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WBP11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 641 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WBP11

Target: WBP11 (WW Domain Binding Protein 11 (WBP11))

Alternative Name: WBP11 (WBP11 Products)

Synonyms: 2510026P17Rik antibody, D6Wsu113e antibody, Npwbp antibody, SIPP1 antibody, MGC69268 antibody, SNP70 antibody, zgc:77390 antibody, NPWBP antibody, WBP-11 antibody, WW domain binding protein 11 antibody, WW domain binding protein 11 S homeolog antibody, Wbp11 antibody, WBP11 antibody, wbp11.S antibody, wbp11 antibody, Tsp_13063 antibody

Background: WBP11 is a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. WBP11has 95 % amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95 % amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.
Alias Symbols: DKFZp779M1063, NPWBP, SIPP1, WBP-11
Protein Interaction Partner: TESC, TRAF4, GRB2, FYN, UBC, BMI1, APBB1, WBP4, HECW2, DDX17, RBM5, PPP1CA, DDX5, CTNNBL1, PPP1CC, UPF3B, ZC3H13, CPSF6, SNRPB2, PQBP1, CD2BP2, SF3A2, ITSN1, RTN4IP1, PPP1CB, GIGYF2, MCRS1, PRPF40A, C5orf22, NCK2, TRIP10, NCF1, VIM, SRC, PIK3R1, RUNX1T1,
Protein Size: 641

Molecular Weight: 70 kDa

Gene ID: 51729

NCBI Accession: NM_016312, NP_057396

UniProt: Q9Y2W2