GINS2 antibody (N-Term)

Catalog No. ABIN2782555

Product Details anti-GINS2 Antibody

Target: GINS2 (GINS Complex Subunit 2 (Psf2 Homolog) (GINS2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GINS2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DAAEVEFLAE KELVTIIPNF SLDKIYLIGG DLGPFNPGLP VEVPLWLAIN

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 93%, Pig: 93%, Rat: 93%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GINS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GINS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 185 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GINS2

Target: GINS2 (GINS Complex Subunit 2 (Psf2 Homolog) (GINS2))

Alternative Name: GINS2 (GINS2 Products)

Background: The yeast heterotetrameric GINS complex is made up of Sld5, Psf1, Psf2, and Psf3. The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts.The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4, MIM 610611), Psf1 (GINS1, MIM 610608), Psf2, and Psf3 (GINS3, MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM].
Alias Symbols: HSPC037, PSF2, Pfs2
Protein Interaction Partner: GINS4, CNDP2, FERMT2, AHSA1, EIF4H, RPS6KA1, CTSA, PEPD, MVD, GSR, EEF2, CASP7, CAPN1, UBC, GINS3, GINS1, FANCF, CHEK2,
Protein Size: 185

Molecular Weight: 21 kDa

Gene ID: 51659

NCBI Accession: NM_016095, NP_057179

UniProt: Q9Y248

Pathways: DNA Replication, Synthesis of DNA