NCAPD2 antibody (C-Term)

Catalog No. ABIN2782540

Product Details anti-NCAPD2 Antibody

Target: NCAPD2 (Non-SMC Condensin I Complex, Subunit D2 (NCAPD2))

Binding Specificity: C-Term

Reactivity: Human, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCAPD2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KAIIDEFEQK LRACHTRGLD GIKELEIGQA GSQRAPSAKK PSTGSRYQPL

Predicted Reactivity: Dog: 79%, Horse: 93%, Human: 100%, Pig: 92%, Rabbit: 92%

Characteristics: This is a rabbit polyclonal antibody against NCAPD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NCAPD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1401 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NCAPD2

Target: NCAPD2 (Non-SMC Condensin I Complex, Subunit D2 (NCAPD2))

Alternative Name: NCAPD2 (NCAPD2 Products)

Synonyms: CAP-D2 antibody, CNAP1 antibody, hCAP-D2 antibody, 2810406C15Rik antibody, 2810465G24Rik antibody, mKIAA0159 antibody, RGD1562596 antibody, im:6902697 antibody, si:dkey-175g20.1 antibody, wu:fc13f08 antibody, wu:fx06e10 antibody, non-SMC condensin I complex subunit D2 antibody, non-SMC condensin I complex, subunit D2 antibody, non-SMC condensin I complex subunit D2 S homeolog antibody, condensin complex subunit 1 antibody, NCAPD2 antibody, Ncapd2 antibody, ncapd2.S antibody, CIMG_02087 antibody, BDBG_08990 antibody, MCYG_08389 antibody, VDBG_09812 antibody, MGYG_05811 antibody, ncapd2 antibody

Background: NCAPD2 is the regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. NCAPD2 may target the condensin complex to DNA via its C-terminal domain.
Alias Symbols: CAP-D2, CNAP1, KIAA0159, hCAP-D2
Protein Interaction Partner: UBC, NCAPG, CCAR2, NCAPH, SMC2, SMC4, TXNL1, RABEP1, PABPC4, RPS5, FLNC, SOX2, CSNK2A1, PAXIP1, PNPT1, NUP153, MEA1, HSPD1, C1QBP, SIRT7, CDK1, RAD21, SIRT3, tat, PARP1,
Protein Size: 1401

Molecular Weight: 157 kDa

Gene ID: 9918

NCBI Accession: NM_014865, NP_055680

UniProt: Q15021