MAGEA6 antibody (Middle Region)

Catalog No. ABIN2782499

Product Details anti-MAGEA6 Antibody

Target: MAGEA6 (Melanoma Antigen Family A, 6 (MAGEA6))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: APEEKIWEEL SVLEVFEGRE DSIFGDPKKL LTQYFVQENY LEYRQVPGSD

Predicted Reactivity: Dog: 83%, Horse: 83%, Human: 100%, Mouse: 83%, Pig: 83%, Rabbit: 83%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against MAGEA6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAGEA6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 314 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAGEA6

Target: MAGEA6 (Melanoma Antigen Family A, 6 (MAGEA6))

Alternative Name: MAGEA6 (MAGEA6 Products)

Synonyms: Mage-a6 antibody, CT1.6 antibody, MAGE-3b antibody, MAGE3B antibody, MAGE6 antibody, melanoma antigen, family A, 6 antibody, MAGE family member A6 antibody, Magea6 antibody, MAGEA6 antibody

Background: MAGEA6 gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: MAGE-3b, MAGE3B, MAGE6, MGC52297, CT1.6
Protein Interaction Partner: KLHL38, MORN3, LCORL, IQUB, MIPOL1, ANKRD26P1, SNAP47, HAUS1, ATPAF2, ELMOD3, RASSF4, SH2D4A, LSM2, CCDC146, STAMBPL1, S100A14, FAM214A, LIN37, RCOR3, GFOD1, FRMPD1, ACOT7, EXOC5, BET1, TXNDC9, AKAP9, ATP6V1G1, BCL7B, SNX4, NCK2, TULP3, STX5, RPL37A, PDE4
Protein Size: 314

Molecular Weight: 35 kDa

Gene ID: 4105

NCBI Accession: NM_005363, NP_005354

UniProt: P43360