HIST1H1C antibody (Middle Region)

Catalog No. ABIN2782497

Product Details anti-HIST1H1C Antibody

Target: HIST1H1C (Histone Cluster 1, H1c (HIST1H1C))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H1C antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Sequence: ASGSFKLNKK AASGEAKPKV KKAGGTKPKK PVGAAKKPKK AAGGATPKKS

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 85%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against HIST1H1C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HIST1H1C

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 213 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HIST1H1C

Target: HIST1H1C (Histone Cluster 1, H1c (HIST1H1C))

Alternative Name: HIST1H1C (HIST1H1C Products)

Synonyms: H1.2 antibody, H1C antibody, H1F2 antibody, H1s-1 antibody, 0610008C09Rik antibody, H1c antibody, H1f2 antibody, H1var1 antibody, His1a antibody, histone cluster 1 H1 family member c antibody, histone cluster 1, H1c antibody, HIST1H1C antibody, Hist1h1c antibody

Background: Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H1.2, H1F2, MGC3992, H1C
Protein Interaction Partner: UBC, CEP250, ATRX, HIST1H3A, LEO1, PAF1, CUL4A, POLR2A, MDM2, ASB16, ASB9, SUZ12, EED, RNF2, APEH, SEC24D, TBCD, PARK2, VHL, UBD, ICAM1, CD81, IGSF8, EIF2AK2, ITGA4, IL7R, CSNK2A2, SMURF1, HIST1H2AD, H1FX, COPS5, CAND1, CUL1, CUL2, CUL3, CUL4B, CUL5, NEDD
Protein Size: 213

Molecular Weight: 21 kDa

Gene ID: 3006

NCBI Accession: NM_005319, NP_005310

UniProt: P16403