NOLC1 antibody (C-Term)

Catalog No. ABIN2782491

Product Details anti-NOLC1 Antibody

Target: NOLC1 (Nucleolar and Coiled-Body Phosphoprotein 1 (NOLC1))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Dog, Goat, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOLC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DNSFDAKRGA AGDWGERANQ VLKFTKGKSF RHEKTKKKRG SYRGGSISVQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against NOLC1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NOLC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 699 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NOLC1

Target: NOLC1 (Nucleolar and Coiled-Body Phosphoprotein 1 (NOLC1))

Alternative Name: NOLC1 (NOLC1 Products)

Background: Related to nucleologenesis, NOLC1 may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. NOLC1 may play an important role in transcription catalyzed by RNA polymerase I.
Alias Symbols: KIAA0035, NOPP130, NOPP140, NS5ATP13, P130
Protein Interaction Partner: UBC, SUMO1, ERG, WWOX, SUZ12, EED, RNF2, RABEP2, CD2AP, SPAG9, YWHAQ, YWHAE, CSNK2A2, PAN2, gag, PNKP, WHSC1, SAP18, G3BP1, GPRC5A, PTRF, NOP58, NOP16, RRP7A, RSL1D1, RRS1, UTP14A, RPL19, RPL18A, RPL15, RPL11, RPL6, RPL5, RPL4, NHP2L1, IK, GTF3C1, FBL, AP
Protein Size: 699

Molecular Weight: 73 kDa

Gene ID: 9221

NCBI Accession: NM_004741, NP_004732

UniProt: Q14978

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling