EPRS antibody (Middle Region)

Catalog No. ABIN2782490

Product Details anti-EPRS Antibody

Target: EPRS (Glutamyl-Prolyl-tRNA Synthetase (EPRS))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPRS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GKIVQIPFCG EIDCEDWIKK TTARDQDLEP GAPSMGAKSL CIPFKPLCEL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against EPRS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EPRS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1512 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EPRS

Target: EPRS (Glutamyl-Prolyl-tRNA Synthetase (EPRS))

Alternative Name: EPRS (EPRS Products)

Synonyms: EARS antibody, GLUPRORS antibody, PARS antibody, QARS antibody, QPRS antibody, wu:fb38d08 antibody, wu:ft34d10 antibody, 2410081F06Rik antibody, 3010002K18Rik antibody, C79379 antibody, Qprs antibody, glutamyl-prolyl-tRNA synthetase antibody, glutamyl-prolyl-tRNA synthetase S homeolog antibody, EPRS antibody, eprs antibody, eprs.S antibody, Eprs antibody

Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. EPRS is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species.Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp313B047, EARS, PARS, PIG32, QARS, QPRS, GLUPRORS
Protein Interaction Partner: HUWE1, ISG15, UBC, AURKA, SUMO2, STAU1, LGR4, RPA3, RPA2, RPA1, SUZ12, RNF2, EZH2, CMYA5, VPS25, LRRC47, LARS, TES, IGF2BP3, LRRFIP1, TCEB2, RPL23A, RFC4, PTBP1, NEDD4, IARS, CDC42, EEF1D, FBXO6, EGFR, UBD, ITGA4, FN1, MAP1LC3A, gag, VCAM1, VBP1, UBA1, TC
Protein Size: 1512

Molecular Weight: 170 kDa

Gene ID: 2058

NCBI Accession: NM_004446, NP_004437

UniProt: P07814