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DFNA5 antibody (C-Term)

DFNA5 Reactivity: Human, Rat, Cow, Dog, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782489
  • Target See all DFNA5 Antibodies
    DFNA5 (Deafness, Autosomal Dominant 5 (DFNA5))
    Binding Specificity
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 30
    • 19
    • 18
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Cow, Dog, Guinea Pig
    Host
    • 42
    • 3
    Rabbit
    Clonality
    • 44
    • 1
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DFNA5 antibody is un-conjugated
    Application
    • 33
    • 18
    • 13
    • 13
    • 10
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    AALLGTCCKL QIIPTLCHLL RALSDDGVSD LEDPTLTPLK DTERFGIVQR
    Predicted Reactivity
    Cow: 85%, Dog: 77%, Guinea Pig: 83%, Human: 100%, Rat: 85%
    Characteristics
    This is a rabbit polyclonal antibody against DFNA5. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human DFNA5
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  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 437 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DFNA5 (Deafness, Autosomal Dominant 5 (DFNA5))
    Alternative Name
    DFNA5 (DFNA5 Products)
    Synonyms
    Dfna5h antibody, fk59f08 antibody, zgc:91916 antibody, wu:fc41e05 antibody, wu:fk59f08 antibody, MGC83660 antibody, ICERE-1 antibody, 2310037D07Rik antibody, 4932441K13Rik antibody, EG14210 antibody, Fin15 antibody, gasdermin E antibody, gasdermin Eb antibody, DFNA5, deafness associated tumor suppressor antibody, gasdermin E L homeolog antibody, Gsdme antibody, gsdmeb antibody, DFNA5 antibody, gsdme.L antibody, GSDME antibody
    Background
    Hearing impairment is a heterogeneous condition with over 40 loci described. DFNA5 is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in its gene.
    Alias Symbols: ICERE-1
    Protein Interaction Partner: UBC, EGFR, PTN,
    Protein Size: 437
    Molecular Weight
    47 kDa
    Gene ID
    1687
    NCBI Accession
    NM_001127453
    UniProt
    A4FVA8
    Pathways
    Sensory Perception of Sound
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