DFNA5 antibody (C-Term)

Catalog No. ABIN2782489

Product Details anti-DFNA5 Antibody

Target: DFNA5 (Deafness, Autosomal Dominant 5 (DFNA5))

Binding Specificity: C-Term

Reactivity: Human, Rat, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DFNA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AALLGTCCKL QIIPTLCHLL RALSDDGVSD LEDPTLTPLK DTERFGIVQR

Predicted Reactivity: Cow: 85%, Dog: 77%, Guinea Pig: 83%, Human: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against DFNA5. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DFNA5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 437 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DFNA5

Target: DFNA5 (Deafness, Autosomal Dominant 5 (DFNA5))

Alternative Name: DFNA5 (DFNA5 Products)

Synonyms: Dfna5h antibody, fk59f08 antibody, zgc:91916 antibody, wu:fc41e05 antibody, wu:fk59f08 antibody, MGC83660 antibody, ICERE-1 antibody, 2310037D07Rik antibody, 4932441K13Rik antibody, EG14210 antibody, Fin15 antibody, gasdermin E antibody, gasdermin Eb antibody, DFNA5, deafness associated tumor suppressor antibody, gasdermin E L homeolog antibody, Gsdme antibody, gsdmeb antibody, DFNA5 antibody, gsdme.L antibody, GSDME antibody

Background: Hearing impairment is a heterogeneous condition with over 40 loci described. DFNA5 is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in its gene.
Alias Symbols: ICERE-1
Protein Interaction Partner: UBC, EGFR, PTN,
Protein Size: 437

Molecular Weight: 47 kDa

Gene ID: 1687

NCBI Accession: NM_001127453

UniProt: A4FVA8

Pathways: Sensory Perception of Sound