ATIC antibody (N-Term)

Catalog No. ABIN2782481

Product Details anti-ATIC Antibody

Target: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Cow, Guinea Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATIC antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YVVVSTEMQS SESKDTSLET RRQLALKAFT HTAQYDEAIS DYFRKQYSKG

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against ATIC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATIC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 592 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATIC

Target: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Alternative Name: ATIC (ATIC Products)

Background: ATIC is a bifunctional protein requiring dimerization for transformylase activity.
Alias Symbols: AICAR, AICARFT, IMPCHASE, PURH
Protein Interaction Partner: UBC, NEDD8, SUMO1, ASB6, TATDN1, NSFL1C, OGFOD1, STK26, ISOC1, MCTS1, PROSC, PAPSS1, NAE1, YWHAE, UBA1, PTMA, PAFAH1B1, MYO1E, MSN, IPO5, FH, CTH, CAPN2, AHCY, GMDS, TARDBP, TYMS, TXN, SUMO2, RBBP6, OXCT1, CRK, CLNS1A, CDK2, ISG15, SIRT7, EGFR, ATIC, CMBL
Protein Size: 592

Molecular Weight: 64 kDa

Gene ID: 471

NCBI Accession: NM_004044, NP_004035

UniProt: P31939