ATIC antibody (Middle Region)

Catalog No. ABIN2782480

Product Details anti-ATIC Antibody

Target: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Cow, Pig, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATIC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RTLFGLHLSQ KRNNGVVDKS LFSNVVTKNK DLPESALRDL IVATIAVKYT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%

Characteristics: This is a rabbit polyclonal antibody against ATIC. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATIC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 281 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATIC

Target: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Alternative Name: ATIC (ATIC Products)

Synonyms: AICAR antibody, AICARFT antibody, IMPCHASE antibody, PURH antibody, purH antibody, 2610509C24Rik antibody, AA536954 antibody, AW212393 antibody, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase L homeolog antibody, bifunctional purine biosynthesis protein PurH antibody, bifunctional purine biosynthesis protein purH antibody, Bifunctional purine biosynthesis protein purH antibody, Bifunctional purine biosynthesis protein PurH antibody, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase antibody, atic.L antibody, purH antibody, ATIC antibody, Atic antibody

Background: ATIC is a bifunctional protein requiring dimerization for transformylase activity.
Alias Symbols: AICAR, AICARFT, FLJ93545, IMPCHASE, PURH
Protein Interaction Partner: UBC, NEDD8, SUMO1, ASB6, TATDN1, NSFL1C, OGFOD1, STK26, ISOC1, MCTS1, PROSC, PAPSS1, NAE1, YWHAE, UBA1, PTMA, PAFAH1B1, MYO1E, MSN, IPO5, FH, CTH, CAPN2, AHCY, GMDS, TARDBP, TYMS, TXN, SUMO2, RBBP6, OXCT1, CRK, CLNS1A, CDK2, ISG15, SIRT7, EGFR, ATIC, CMBL
Protein Size: 281

Molecular Weight: 30 kDa

Gene ID: 471

NCBI Accession: NM_004044

UniProt: P31939