PEX3 antibody (N-Term)

Catalog No. ABIN2782478

Product Details anti-PEX3 Antibody

Target: PEX3 (Peroxisomal Biogenesis Factor 3 (PEX3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KYGQKKIREI QEREAAEYIA QARRQYHFES NQRTCNMTVL SMLPTLREAL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PEX3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PEX3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 373 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PEX3 antibody (ABIN2782478)

Libby, Bales, Orlicky, McManaman: "Perilipin-2 Deletion Impairs Hepatic Lipid Accumulation by Interfering with Sterol Regulatory Element-binding Protein (SREBP) Activation and Altering the Hepatic Lipidome." in: The Journal of biological chemistry, Vol. 291, Issue 46, pp. 24231-24246, (2016) (PubMed).

Target Details for PEX3

Target: PEX3 (Peroxisomal Biogenesis Factor 3 (PEX3))

Alternative Name: PEX3 (PEX3 Products)

Synonyms: DDBDRAFT_0204086 antibody, DDBDRAFT_0238047 antibody, DDB_0204086 antibody, DDB_0238047 antibody, zgc:56313 antibody, PBD10A antibody, TRG18 antibody, Peroxin-3 antibody, 1700014F15Rik antibody, 2810027F19Rik antibody, 2900010N04Rik antibody, peroxisomal biogenesis factor 3 antibody, peroxin 3 antibody, peroxisomal biogenesis factor 3 L homeolog antibody, LOC692959 antibody, CpipJ_CPIJ013204 antibody, pex3 antibody, PEX3 antibody, pex3.L antibody, Pex3 antibody

Background: PEX3 is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, it is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
Alias Symbols: TRG18
Protein Interaction Partner: UBC, PEX19, PEX14, CHCHD4, HNRNPR, ABCD3, HNRNPF, DHX15, ABCD1,
Protein Size: 373

Molecular Weight: 42 kDa

Gene ID: 8504

NCBI Accession: NM_003630, NP_003621

UniProt: P56589