PPAT antibody (C-Term)

Catalog No. ABIN2782472

Product Details anti-PPAT Antibody

Target: PPAT (Phosphoribosyl Pyrophosphate Amidotransferase (PPAT))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPAT antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QEGIKFKKQK EKKHDIMIQE NGNGLECFEK SGHCTACLTG KYPVELEW

Predicted Reactivity: Dog: 92%, Horse: 77%, Human: 100%, Mouse: 86%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against PPAT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PPAT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 517 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPAT

Target: PPAT (Phosphoribosyl Pyrophosphate Amidotransferase (PPAT))

Alternative Name: PPAT (PPAT Products)

Background: PPAT is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. Its gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4.The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. This gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4.The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. This gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4.
Alias Symbols: ATASE, GPAT, PRAT
Protein Interaction Partner: FAM96B, CIAO1, FAM114A1, PARVA, CARM1, RANBP3, TROVE2, RSU1, MEA1, ILK, HSPA4, GART, CARS, MMS19, EPT1, ATXN1, SMURF1, MCM3, UBC,
Protein Size: 517

Molecular Weight: 56 kDa

Gene ID: 5471

NCBI Accession: NM_002703, NP_002694

UniProt: Q06203