CTP Synthase antibody (N-Term)
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- Target See all CTP Synthase (CTPS) Antibodies
- CTP Synthase (CTPS)
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CTP Synthase antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- SMPFIEAFRQ FQFKVKRENF CNIHVSLVPQ PSSTGEQKTK PTQNSVRELR
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against CTPS. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CTPS
- Top Product
- Discover our top product CTPS Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 591 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CTP Synthase (CTPS)
- Alternative Name
- CTPS (CTPS Products)
- Background
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The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis.The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types.The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types.
Alias Symbols: CTPS
Protein Interaction Partner: UBC, CTPS1, TUBGCP3, AURKA, SUMO2, SUMO3, SUMO1, NEDD8, DCTPP1, GINS3, UBA6, UBXN1, PAPSS1, VCL, UBA1, PPP5C, PKM, DFFA, CS, CLNS1A, ACO1, YWHAQ, MYC, RBM28, POLR1C, FBXO6, CAND1, COPS5, CUL1, CUL2, CUL3, CUL4B, CUL5, CDK2, ARRB2, RAD21, PSMA3, YWHAG, TRA
Protein Size: 591 - Molecular Weight
- 67 kDa
- Gene ID
- 1503
- NCBI Accession
- NM_001905, NP_001896
- UniProt
- P17812
- Pathways
- Proton Transport, Ribonucleoside Biosynthetic Process
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