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GM2A antibody (N-Term)

GM2A Reactivity: Human, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782426
  • Target See all GM2A Antibodies
    GM2A (GM2 Ganglioside Activator (GM2A))
    Binding Specificity
    • 15
    • 11
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 60
    • 21
    • 20
    • 1
    Human, Guinea Pig
    Host
    • 54
    • 7
    • 2
    Rabbit
    Clonality
    • 58
    • 5
    Polyclonal
    Conjugate
    • 27
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GM2A antibody is un-conjugated
    Application
    • 49
    • 28
    • 13
    • 13
    • 11
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    SWDNCDEGKD PAVIRSLTLE PDPIIVPGNV TLSVMGSTSV PLSSPLKVDL
    Predicted Reactivity
    Guinea Pig: 83%, Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against GM2A. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human GM2A
    Top Product
    Discover our top product GM2A Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 193 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    GM2A (GM2 Ganglioside Activator (GM2A))
    Alternative Name
    GM2A (GM2A Products)
    Synonyms
    GM2A antibody, fb96e04 antibody, fb96e10 antibody, wu:fb96e04 antibody, wu:fb96e10 antibody, zgc:110188 antibody, MGC84154 antibody, GM2-AP antibody, SAP-3 antibody, AA408702 antibody, AW215435 antibody, GM2 ganglioside activator antibody, GM2 ganglioside activator L homeolog antibody, GM2 ganglioside activator protein antibody, Gm2a antibody, GM2A antibody, gm2a antibody, gm2a.L antibody
    Background
    This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
    Alias Symbols: SAP-3, GM2-AP
    Protein Interaction Partner: ELAVL1, UBC, HEXA, GPLD1, PLD2,
    Protein Size: 193
    Molecular Weight
    21 kDa
    Gene ID
    2760
    NCBI Accession
    NM_000405, NP_000396
    UniProt
    P17900
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