DONSON antibody (Middle Region)

Catalog No. ABIN2782388

Product Details anti-DONSON Antibody

Target: DONSON (Downstream Neighbor of SON (DONSON))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Guinea Pig, Horse, Rabbit, Cow, Dog, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DONSON antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DLITALISPT TRGLREAMRN EGIEFSLPLI KESGHKKETA SGTSLGYGEE

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DONSON. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DONSON

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 566 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-DONSON antibody (ABIN2782388)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Target Details for DONSON

Target: DONSON (Downstream Neighbor of SON (DONSON))

Alternative Name: DONSON (DONSON Products)

Background: This gene lies downstream of the SON gene and spans 10 kb on chromosome 21. The function of this gene is unknown.This gene lies downstream of the SON gene and spans 10 kb on chromosome 21. The function of this gene is unknown.
Alias Symbols: B17, C21orf60, DKFZP434M035, C2TA
Protein Interaction Partner: UBC, PSMA3,
Protein Size: 566

Molecular Weight: 63 kDa

Gene ID: 29980

NCBI Accession: NM_017613, NP_060083

UniProt: Q9NYP3