SUMO3 antibody (N-Term)

Catalog No. ABIN2782380

Product Details anti-SUMO3 Antibody

Target: SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUMO3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PKEGVKTEND HINLKVAGQD GSVVQFKIKR HTPLSKLMKA YCERQGLSMR

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Sumo3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Sumo3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 110 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SUMO3

Target: SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))

Alternative Name: Sumo3 (SUMO3 Products)

Background: Sumo3 is a ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. It does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. It plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.
Alias Symbols: 2810014B19Rik, AA409334, AW121497, AW536077, D10Ertd345e, SMT3A, SUMO-3, Smt3h1, Smt3B
Protein Interaction Partner: Ep300, Senp6, Ikbkg, Npm1, Mdm2, Uimc1, Mafg,
Protein Size: 110

Molecular Weight: 12 kDa

Gene ID: 20610

NCBI Accession: NM_019929, NP_064313

UniProt: Q9Z172