CCT8 antibody (C-Term)

Catalog No. ABIN2782379

Product Details anti-CCT8 Antibody

Target: CCT8 (Chaperonin Containing TCP1, Subunit 8 (Theta) (CCT8))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DMLEAGILDT YLGKYWAIKL ATNAAVTVLR VDQIIMAKPA GGPKPPSGKK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CCT8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CCT8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 548 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CCT8 antibody (ABIN2782379)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Suzuki, Yoshitomo-Nakagawa, Maruyama, Suyama, Sugano: "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." in: Gene, Vol. 200, Issue 1-2, pp. 149-56, (1997) (PubMed).

Target Details for CCT8

Target: CCT8 (Chaperonin Containing TCP1, Subunit 8 (Theta) (CCT8))

Alternative Name: CCT8 (CCT8 Products)

Synonyms: CCT8 antibody, DKFZp469C2223 antibody, MGC89698 antibody, C21orf112 antibody, Cctq antibody, D21S246 antibody, PRED71 antibody, AI132397 antibody, Tcpq antibody, fa22h09 antibody, wu:fa22h09 antibody, zgc:56059 antibody, chaperonin containing TCP1 subunit 8 antibody, chaperonin containing TCP1, subunit 8 (theta) antibody, chaperonin containing Tcp1, subunit 8 (theta) antibody, chaperonin containing TCP1 subunit 8 L homeolog antibody, Chaperonin Containing TCP-1 antibody, CCT8 antibody, cct8 antibody, Cct8 antibody, cct8.L antibody, cct-8 antibody

Background: As a molecular chaperone, CCT8 assists the folding of proteins upon ATP hydrolysis. It is known to play a role, in vitro, in the folding of actin and tubulin.
Alias Symbols: Cctq, D21S246, KIAA0002, PRED71, C21orf112
Protein Interaction Partner: FUS, HUWE1, UBC, TP53, TUBG1, SUMO3, LGALS3BP, NEDD1, CDC20, SUMO1, NEDD8, MDM2, ASB13, CCT5, CCT2, CCT7, CCT6A, FBXO6, UBD, FBXW4, HDAC3, STK24, ILK, CDK9, CDK5, CDK2, PAN2, FN1, METTL21B, TP63, VCAM1, PEX14, NOS2, ITGA4, US3, FAM86B2, METTL20, METTL18,
Protein Size: 548

Molecular Weight: 59 kDa

Gene ID: 10694

NCBI Accession: NM_006585, NP_006576

UniProt: Q5RAP1