RRP1 antibody (C-Term)

Catalog No. ABIN2782369

Product Details anti-RRP1 Antibody

Target: RRP1 (Ribosomal RNA Processing 1 Homolog A (RRP1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: IPEKACRRLL EGRRQKKTKK QKRLLRLQQE RGKGEKEPPS PGMERKRSRR

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against RRP1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RRP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 461 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-RRP1 antibody (ABIN2782369)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Target Details for RRP1

Target: RRP1 (Ribosomal RNA Processing 1 Homolog A (RRP1))

Alternative Name: RRP1 (RRP1 Products)

Synonyms: D21S2056E antibody, NNP-1 antibody, NOP52 antibody, RRP1A antibody, Nnp1 antibody, AL033305 antibody, AL033306 antibody, AU018604 antibody, ribosomal RNA processing 1 antibody, ribosomal RNA processing 1 homolog (S. cerevisiae) antibody, RRP1 antibody, Rrp1 antibody

Background: RRP1 is the putative homolog of the yeast ribosomal RNA processing protein RRP1. The protein is involved in the late stages of nucleologenesis at the end of mitosis, and may be required for the generation of 28S rRNA.The protein encoded by this gene is the putative homolog of the yeast ribosomal RNA processing protein RRP1. The encoded protein is involved in the late stages of nucleologenesis at the end of mitosis, and may be required for the generation of 28S rRNA.
Alias Symbols: D21S2056E, NNP-1, NOP52, RRP1A
Protein Interaction Partner: UBC, RNF2, PAN2, WHSC1, BARD1, SIRT7,
Protein Size: 461

Molecular Weight: 53 kDa

Gene ID: 8568

NCBI Accession: NM_003683, NP_003674

UniProt: P56182