USP16 antibody (N-Term)

Catalog No. ABIN2782358

Product Details anti-USP16 Antibody

Target: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Pig, Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP16 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: CKTDNKVKDK AEEETEEKPS VWLCLKCGHQ GCGRNSQEQH ALKHYLTPRS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 92%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against USP16. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human USP16

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 408 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for USP16

Target: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Alternative Name: USP16 (USP16 Products)

Synonyms: ubp-m antibody, USP16 antibody, UBP-M antibody, 1200004E02Rik antibody, 2810483I07Rik antibody, 6330514E22Rik antibody, UBPM antibody, si:ch211-238e22.5 antibody, si:dkey-121n8.2 antibody, wu:fc76b02 antibody, wu:fc76b08 antibody, universal stress protein antibody, ubiquitin specific peptidase 16 antibody, ubiquitin specific peptidase 16 L homeolog antibody, usp16 antibody, USP16 antibody, Usp16 antibody, usp16.L antibody

Background: USP16 is a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division.
Alias Symbols: UBP-M
Protein Interaction Partner: RNF8, HERC2, USP16, HIST1H2AB, XPO1, HIST1H2BB, CDK1, HIST2H2AC, HIST2H2AA3, UBC, IGF2BP3, TXNL1, CSNK1D, HIST4H4, FBXO11, PTOV1, UBD, hist1h3g, CALM1, HIST1H2BL, DBT, EXOSC10,
Protein Size: 408

Molecular Weight: 44 kDa

Gene ID: 10600

NCBI Accession: NM_001001992

UniProt: Q5VKN8