SBDS antibody (C-Term)

Catalog No. ABIN2782337

Product Details anti-SBDS Antibody

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Zebrafish (Danio rerio), Cow, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SBDS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DYGQQLEIVC LIDPGCFREI DELIKKETKG KGSLEVLNLK DVEEGDEKFE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against SBDS. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SBDS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 250 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SBDS

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Alternative Name: SBDS (SBDS Products)

Synonyms: cgi-97 antibody, sds antibody, swds antibody, zgc:56700 antibody, SDS antibody, SWDS antibody, 4733401P19Rik antibody, AI836084 antibody, CGI-97 antibody, SBDS ribosome assembly guanine nucleotide exchange factor antibody, hypothetical protein antibody, SBDS, ribosome maturation factor antibody, SBDS ribosome assembly guanine nucleotide exchange factor S homeolog antibody, SBDS ribosome maturation factor antibody, sbds antibody, LOAG_04440 antibody, sbds.S antibody, SBDS antibody, Sbds antibody

Background: SBDS is a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The protein may function in RNA metabolism. Mutations within its gene are associated with Shwachman-Bodian-Diamond syndrome.This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located.
Alias Symbols: CGI-97, FLJ10917, SDS, SWDS
Protein Interaction Partner: SUMO2, TYMS, PNP, IDH1, GOT1, UBC, CHAMP1, MPLKIP, MRPL53, SARNP, SLIRP, SRPRB, ACOT13, SRRM2, TIMM44, TOMM40, UBE4B, SCO2, SNX3, STX7, SF1, VDAC3, TIAL1, SPR, RBMS1, NDUFA7, NDUFA2, IDH3G, STOM, ACAA1, ACD, TERF2IP, POT1, TERF1, CLN3,
Protein Size: 250

Molecular Weight: 28 kDa

Gene ID: 51119

NCBI Accession: NM_016038, NP_057122

UniProt: Q9Y3A5

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly