MBL2 antibody (Middle Region)

Catalog No. ABIN2782311

Product Details anti-MBL2 Antibody

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Cow, Goat, Sheep, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBL2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KEEAFLGITD EKTEGQFVDL TGNRLTYTNW NEGEPNNAGS DEDCVLLLKN

Predicted Reactivity: Cow: 77%, Goat: 77%, Horse: 92%, Human: 100%, Pig: 92%, Rat: 77%, Sheep: 77%

Characteristics: This is a rabbit polyclonal antibody against MBL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MBL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 248 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MBL2

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Alternative Name: MBL2 (MBL2 Products)

Background: This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
Alias Symbols: COLEC1, HSMBPC, MBL, MBP, MBP1, MGC116832, MGC116833, MBL2D, MBP-C
Protein Interaction Partner: MASP2, MAD2L1, MASP1, MBL2, PTPRC, KRT1, CD93, CALCR, CALR,
Protein Size: 248

Molecular Weight: 24 kDa

Gene ID: 4153

NCBI Accession: NM_000242, NP_000233

UniProt: Q66S64

Pathways: Complement System, Positive Regulation of Immune Effector Process