HNF4 gamma antibody (N-Term)

Catalog No. ABIN2782279

Product Details anti-HNF4 gamma Antibody

Target: HNF4 gamma (HNF4G) (Hepatocyte Nuclear Factor 4 gamma (HNF4G))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF4 gamma antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MDMANYSEVL DPTYTTLEFE TMQILYNSSD SSAPETSMNT TDNGVNCLCA

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against HNF4G. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNF4G

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 445 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HNF4 gamma antibody (ABIN2782279)

Franke, Hampe, Rosenstiel, Becker, Wagner, Häsler, Little, Huse, Ruether, Balschun, Wittig, Elsharawy, Mayr, Albrecht, Prescott, Onnie, Fournier, Keith, Radelof, Platzer, Mathew, Stoll, Krawczak et al.: "Systematic association mapping identifies NELL1 as a novel IBD disease gene. ..." in: PLoS ONE, Vol. 2, Issue 8, pp. e691, (2007) (PubMed).

Target Details for HNF4 gamma

Target: HNF4 gamma (HNF4G) (Hepatocyte Nuclear Factor 4 gamma (HNF4G))

Alternative Name: HNF4G (HNF4G Products)

Synonyms: HNF4G antibody, hnf4gamma antibody, zgc:153265 antibody, NR2A2 antibody, NR2A3 antibody, hepatocyte nuclear factor 4 gamma antibody, hepatocyte nuclear factor 4, gamma antibody, HNF4G antibody, hnf4g antibody, Hnf4g antibody

Background: HNF4 was first identified as a DNA binding activity in rat liver nuclear extracts and then was found to be an orphan member of the nuclear receptor superfamily. Binding sites for this factor were identified in many tissue-specifically expressed genes, and the protein was found to be essential for early embryonic development in the mouse
Alias Symbols: NR2A2, NR2A3
Protein Interaction Partner: NSD1, NCOA1, PNRC2, COPS5, PNRC1, HAX1, RANBP9, PRDX6, EIF3I, NR0B2, TNNI2, SRC, GAPDH, HLF,
Protein Size: 445

Molecular Weight: 50 kDa

Gene ID: 3174

NCBI Accession: NM_004133, NP_004124

UniProt: Q14541

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway