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RORA antibody (Middle Region)

RORA Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Goat, Zebrafish (Danio rerio), Sheep WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782273
  • Target See all RORA Antibodies
    RORA (RAR-Related Orphan Receptor A (RORA))
    Binding Specificity
    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 71
    • 30
    • 29
    • 12
    • 12
    • 9
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Goat, Zebrafish (Danio rerio), Sheep
    Host
    • 66
    • 5
    Rabbit
    Clonality
    • 67
    • 4
    Polyclonal
    Conjugate
    • 45
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RORA antibody is un-conjugated
    Application
    • 55
    • 25
    • 15
    • 10
    • 9
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    GHTPEGSKAD SAVSSFYLDI QPSPDQSGLD INGIKPEPIC DYTPASGFFP
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against RORA. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RORA
    Top Product
    Discover our top product RORA Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 556 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RORA (RAR-Related Orphan Receptor A (RORA))
    Alternative Name
    RORA (RORA Products)
    Synonyms
    ror1 antibody, ror2 antibody, ror3 antibody, rzra antibody, nr1f1 antibody, MGC146531 antibody, NR1F1 antibody, ROR1 antibody, ROR2 antibody, ROR3 antibody, RZR-ALPHA antibody, RZRA antibody, RORalpha-B antibody, gb:dq017624 antibody, rora2 antibody, 9530021D13Rik antibody, Nr1f1 antibody, nmf267 antibody, sg antibody, staggerer antibody, tmgc26 antibody, RORalpha1 antibody, RAR related orphan receptor A antibody, RAR-related orphan receptor A antibody, RAR-related orphan receptor A, paralog a antibody, RAR-related orphan receptor alpha antibody, RORA antibody, rora antibody, Rora antibody, roraa antibody
    Background
    The protein encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.
    Alias Symbols: MGC119326, MGC119329, NR1F1, ROR1, ROR2, ROR3, RZRA, RZR-ALPHA
    Protein Interaction Partner: GFAP, NSD1, NCOA1, PSMC5, SMARCD3, PTBP1, VPRBP, UBC, EZH2, DDB1, LMO3, NR0B1, ZXDC, PNRC2, COPS5, PNRC1, EIF3I, PROX1, LRIF1, RUVBL1, CEBPB, NCOA2, MED1, EP300, RORA, MYOD1, NME2, NME1,
    Protein Size: 556
    Molecular Weight
    63 kDa
    Gene ID
    6095
    NCBI Accession
    NM_134260, NP_599022
    UniProt
    P35398
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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