DEGS1 antibody (N-Term)

Catalog No. ABIN2782243

Product Details anti-DEGS1 Antibody

Target: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio), Cow, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEGS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GSRVSREDFE WVYTDQPHAD RRREILAKYP EIKSLMKPDP NLIWIIIMMV

Predicted Reactivity: Cow: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against DEGS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DEGS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 323 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DEGS1

Target: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Alternative Name: DEGS1 (DEGS1 Products)

Synonyms: DEGS antibody, DEGS-1 antibody, DES1 antibody, Des-1 antibody, FADS7 antibody, MLD antibody, degs antibody, im:6909319 antibody, wu:fa25h01 antibody, wu:fb81d06 antibody, Degs antibody, AA536663 antibody, Des1 antibody, Mdes antibody, delta 4-desaturase, sphingolipid 1 antibody, delta(4)-desaturase, sphingolipid 1 antibody, DEGS1 antibody, degs1 antibody, Degs1 antibody

Background: DEGS1 is a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this protein inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.
Alias Symbols: DEGS, DES1, Des-1, FADS7, MGC5079, MIG15, MLD, DEGS-1
Protein Interaction Partner: UBC, NAGPA, UBD, EGFR, TSSC1, SURF4, SLC16A1, PYGM,
Protein Size: 323

Molecular Weight: 38 kDa

Gene ID: 8560

NCBI Accession: NM_003676, NP_003667

UniProt: O15121