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Transferrin Receptor 2 antibody (Middle Region)

TFR2 Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782222
  • Target See all Transferrin Receptor 2 (TFR2) Antibodies
    Transferrin Receptor 2 (TFR2)
    Binding Specificity
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 30
    • 10
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Pig
    Host
    • 33
    • 6
    Rabbit
    Clonality
    • 25
    • 14
    Polyclonal
    Conjugate
    • 24
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Transferrin Receptor 2 antibody is un-conjugated
    Application
    • 27
    • 20
    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    YVSLDNAVLG DDKFHAKTSP LLTSLIESVL KQVDSPNHSG QTLYEQVVFT
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against TFR2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human TFR2
    Top Product
    Discover our top product TFR2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 801 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Transferrin Receptor 2 (TFR2)
    Alternative Name
    TFR2 (TFR2 Products)
    Synonyms
    TFR2 antibody, Trfr2 antibody, HFE3 antibody, TFRC2 antibody, zgc:123043 antibody, transferrin receptor 2 antibody, TFR2 antibody, Tfr2 antibody, tfr2 antibody
    Background
    TFR2,a member of the transferrin receptor-like family,is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III.This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: HFE3, MGC126368, TFRC2
    Protein Interaction Partner: FBXO6, ATP4A, SOCS3, UBC, HFE, TF,
    Protein Size: 801
    Molecular Weight
    89 kDa
    Gene ID
    7036
    NCBI Accession
    NM_003227, NP_003218
    UniProt
    Q9UP52
    Pathways
    Transition Metal Ion Homeostasis
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