SSR1 antibody (N-Term)

Catalog No. ABIN2782211

Product Details anti-SSR1 Antibody

Target: SSR1 (Signal Sequence Receptor, alpha (SSR1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Dog, Rat, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DDEAEVEEDE PTDLVEDKEE EDVSGEPEAS PSADTTILFV KGEDFPANNI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against SSR1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SSR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 286 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SSR1

Target: SSR1 (Signal Sequence Receptor, alpha (SSR1))

Alternative Name: SSR1 (SSR1 Products)

Background: The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein.The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are exclusively non-canonical.
Alias Symbols: DKFZp781N23103, TRAPA
Protein Interaction Partner: HUWE1, ILK, EDEM1, SERPINF2, SERPINA1, ODC1, MYC, HSPA5, MDC1, SFXN1, HM13, ACAD9, FKBP8, CCT5, CCT2, CCT4, TCP1, SRSF1, PSAP, HNRNPM, ILF3, FLOT2, ABCC2, ATP6V1C1, FBXO6, CAND1, CUL3, ELAVL1, HDGF, UBC, SUMO2, HSPA13, UTP14A, NUP54, DKC1, PTN, EEF1A1,
Protein Size: 286

Molecular Weight: 32 kDa

Gene ID: 6745

NCBI Accession: NM_003144, NP_003135

UniProt: P43307

Pathways: ER-Nucleus Signaling