SOAT1 antibody (Middle Region)

Catalog No. ABIN2782210

Product Details anti-SOAT1 Antibody

Target: SOAT1 (Sterol O-Acyltransferase 1 (SOAT1))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Pig, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOAT1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ASRFIIIFEQ IRFVMKAHSF VRENVPRVLN SAKEKSSTVP IPTVNQYLYF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against SOAT1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SOAT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 550 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOAT1

Target: SOAT1 (Sterol O-Acyltransferase 1 (SOAT1))

Alternative Name: SOAT1 (SOAT1 Products)

Background: Acyl-coenzyme A:cholesterol acyltransferase (ACACT, EC 2.3.1.26) is an intracellular protein located in the endoplasmic reticulum that forms cholesterol esters from cholesterol. Accumulation of cholesterol esters as cytoplasmic lipid droplets within macrophages and smooth muscle cells is a characteristic feature of the early stages of atherosclerotic plaques (Cadigan et al., 1988 [PubMed 3335499]).
Alias Symbols: ACACT, ACAT, ACAT1, RP11-215I23.2, SOAT, STAT
Protein Interaction Partner: UBC, ILF2, SLC25A10, TERF1,
Protein Size: 550

Molecular Weight: 65 kDa

Gene ID: 6646

NCBI Accession: NM_003101, NP_003092

UniProt: P35610